再生医学ジャーナル

Autologous Bone Marrow Derived Cell Concentrate Therapy for Thin Endometrium

Nayana Patel

Objective: To observe that can cell therapy with Autologous Bone Marrow Derived Cell concentrate, post uterine artery injection through interventional radiology offer a therapeutic approach in patients with Thin Endmoetrium. Design: Pilot Study Setting: Referral Centre Patient(s): This was a prospective pilot study of 12 participants ageing from 25 to 45 years old with Thin Endometrium. Intervention: Uterine artery injection of autologous Bone Marrow Derived Cell concentrate through interventional radiology Main outcome measures: Endometrial lining improvement, Emdoemtial Thickness and Increase in Menstrual Blood Flow. Result: All patients exhibited an improvement in Endometrial Linning anf Endometrial Thickness. Also, increase in Menstrual Blood flow was observed. Conclusion: Failure to construct or regenerate a functional endometrium with its correct morphology and thickness in patients with inadequate thin endometrium is believed to be one of the major clinical issues in fertility treatments. With the advancement in regenerative science, clinician can utilize cells (BMDCs) which have high regenerative & repair potential. This is the first of its kind study analyses that cell therapy with Autologous Bone Marrow derived Cell Concentrate has benefitted patients.