国際心臓血管研究ジャーナル

Digital Analytic Cardiography (DACG), a New Method for Quantitative Trophism Assessment of the Myocardium

Alekseyev Michael, Alekseyev Aleksandr, Dowzhikov Andrew and Labin Sergei

 Digital Analytic Cardiography (DACG), a New Method for Quantitative Trophism Assessment of the Myocardium

Background: At present, none of the available ischemic heart disease (IHD) diagnostic methods can reveal the disease with 100% certainty. Methods and Results:DACG, a new method of ECG signal processing, has been utilized to calculate the criteria. We observed 5 groups of patients: 2 control without IHD; one group with IHD, 8 of whom were observed before and after using nitrates; and 2 patients with syndrome X.There were authentic augmentations of all worked-out criteria (G, L, S) in the ischemia zone of the myocardium in relation to the non-ischemic zones (from 2 to 7). In the control, all criteria oscillate from 0 to 1.5. The value of the G criterion has a strict correlation with the functional classification of IHD. We observed a strong correlation between the clinical effect by nitrates and our criteria. The absence of a clinical effect by nitrates correlated with no dynamics in all criteria. The combination of the absence of criteria and clinical effect by nitrates with elevated L criteria led to acute myocardial infarction in a few hours. We developed non-locality in the ischemic process in patients with syndrome X with significant augmentation of the G and L criteria in all zones of the myocardium. Conclusions:The proposed DACG method allows for authentically diagnosing IHD and its functional class impartially, as well as localizing the ischemic process and qualifying its depth quantitatively.