生化学および生理学ジャーナル

Can Renalase Enzyme Control the Fate of Parkinson�??s and Schizophrenia?

Mustafa Ata Aydin and Suleyman Aydin

Dopamine is a catecholamine that is involved in the etiopathology of neurodegenerative diseases like Parkinson’s and schizophrenia. Parkinson’s disease develops as a result of dopamine deficiency in the glial beds of the brain. Schizophrenia, on the other hand, is characterized by excessive dopamine. The limited number of drugs used in Parkinson’s disease either makes up the dopamine deficiency (L-Dopa), or exercise dopamine-like effects, or prevent the breakdown of dopamine in the brain.