歯の健康: 現在の研究

Use of Biosilicate® to Treat Bone Defects due to Periapical Disease: A Case Report

Marcelo Donizetti Chaves, Liciane Bello, Angela Maria Paiva Magri, Murilo C. Crovace and Ana Claudia M Renno

Periapical inflammatory lesion is one of the most prevalent diseases in general dental practices. Many consequences are related to this disease including the appearance of bone defects. In this context, treatments able of stimulating bone tissue have been developed, including osteogenic biomaterials. This pilot case study aimed to evaluate the effects of Biosilicate® in the process of healing in bone defects due to periapical disease. A 53-year-old woman, with recurrent episodes of acute exacerbation of an inflammatory chronic process in the apex of the maxillary left lateral incisor (MLLI), presenting endodontic retreatment and intracanal pin, was studied. Biosilicate® was implanted in the area of the defect and the treatment was analyzed by radiographic examinations (immediately post-surgery, and then 1, 3 and 6 months afterwards). Postoperative pain and swelling were negligible and soft tissue healing was very fast. A higher intensity of pixels in the radiographic examination was observed in the region of the injury after surgery indicating that the material remained in the defect. One month after surgery, the opacity decreased compared to the baseline evaluation, followed by a constant increase 3 and 6 months after surgery. Biosilicate® improved the bone regenerative process, reduced postoperative symptoms and stimulated the deposition of newly formed bone in the area of the bone defect.