細胞生物学: 研究と治療

A Modular Network Regulates Longevity of Chronologically Aging Yeast

Adam Beach, Michelle T. Burstein, Vincent R. Richard, Alejandra Gomez-Perez, Anna Leonov, Tatiana Iouk and Vladimir I. Titorenko

A Modular Network Regulates Longevity of Chronologically Aging Yeast

The fundamental mechanisms of aging are conserved across phyla. Aging of multicellular eukaryotic organisms affects numerous processes within cells. A challenge is to understand how cells integrate and control these processes. The yeast Saccharomyces cerevisiae, a genetically and biochemically manipulable unicellular eukaryote with annotated genome, is a valuable model for unveiling mechanisms of cellular aging in multicellular eukaryotes.